Vol. 4, Issue 3 (2019)
Stem cell banking: A global view
Author(s): Anushi Singh
Abstract: Stem cell banking has been a topic of discussion and debate for more than a decade since the first public services to supply human embryonic stem cells (hESCs) were established This topic has received a recent revival with numerous ambitious programmes announced to deliver large collections of human induced pluripotency cell (hiPSC) lines. Embryonic stem cells are pluripotent stem cells which can give rise to all of the cell types that make up the body; embryonic stem cells derived from the inner cell mass of a blastocyst, an early-stage preimplantation embryo. Adult stem cells have demonstrated tremendous human therapeutic potential. Currently, human embryonic stem cells are used principally for understanding growth and disease development but also hold enormous medicinal potential. The capability to preserve stem cells is difficult for their use in medical applications. Preservation of cells allows the movement of cells between sites, as well as completion of safety and quality testing. Preservation allows the development of a ‘manufacturing paradigm’ for cell therapies, thereby maximizing the number of products that can be produced at a given facility. Different modes of preservation and the current status of preservation of hematopoietic, mesenchymal and human embryonic stem cells can be studied in this article. This article will provide a brief overview charting the development of stem cell banks, their value, and their likely role in the future.