Production and potential applications of Egg Yolk antibodies (Igy) as anti-bacterial prophylactic uses for infectious diseases
T Kumaran, T Citarasu
Immunoglobulin Y (IgY) is the major antibody pro¬duced by chickens (Gallus gallus domesticus). It is con¬tinually synthesized at a large scale, secreted into the blood and transferred to the egg yolk, where it accumu¬lates. To obtain specific IgY antibod¬ies against an antigen of interest, egg-laying hens are immunized with the antigen; following this, antibodies are purified from their egg yolks. IgY purification is an easy, fast and low-cost isolation pro¬cess that produces a high quantity of specific antibody. IgY can be used in various immunological as¬says and may offer better results than traditionally used mammalian antibodies The yolks of eggs laid by immunized chicken have been recognized as an excellent source of polyclonal antibodies for over a decade. This simple noninvasive approach presents an appealing alternative to conventional polyclonal antibody production methods. This review offers summarized information about egg yolks from immunized hens may be a reliable source for antibody production, which can be employed for immunological studies.