Diabetes mellitus is a global emergency, some 415 million people worldwide, are estimated to have diabetes. People with diabetes are at higher risk of developing a number of disabling and life threatening health problems. A quantitative study was conducted to assess the effectiveness of structured teaching programme in terms of knowledge regarding diabetic foot care among diabetic patients. To evaluate the effectiveness of structured teaching programme, a pre experimental, one group pre-test post-test research design was carried out on 30 diabetic patients of Bombay Hospital, Indore. Self-administered close ended questionnaire were used to assess the knowledge regarding diabetic foot care before and after administering structured teaching programme. The results showed that there was significant difference between pre-test and post-test knowledge score, as calculated t value 8.89 revealed p<0.05.