Introduction: The aim of present study to assess the effectiveness of lidocaine spray by comparing the pain levels without lidocaine spray and with lidocaine spray. Materials and methods: Quantitative research approach with pre-experimental research design was adopted for the study which was conducted in selected PHC, Saroor nagar, Hyderabad, Ap”. 30 adult clients between 18-45 years was recruited in study by purposive sampling technique. Wong baker pain rating scale was used to measure pre and Post Test pain levels. Data was analysed by using descriptive and inferential statistics. Percentages of categorical variable were computed. Results: In the present study, regarding pretest level of pain is assessed by using standerdised wong baker pain rating scale, and the level of pain categories as Pre Test - no pain – 0%, mild pain – 4(13.33%), moderate pain – 20(66.7%) and severe pain – 6(20%) and regarding Post Test level of pain as no pain – 4(13.33%), mild pain – 20(80.00%), moderate pain – 2(6.67%) and severe pain – 0% . The obtained 't'-test value for pain level is significant. The adult clients Post Test pain levels of intramuscular injection decreased as compared to pre-test and the lidocaine spray has the effectiveness in reducing pain of intramuscular injection. Conclusion: The findings show that there was a significant difference in pre-test and post-test pain levels. The lidocaine spray is effective in reducing pain of Intramuscular injection.