The paper deals the Phytochemical analysis of leaf of Coleus forskohlii. It is cultivated in India and China for medicinal purpose. It is used as various folk medicine. Hence, the plant Coleus forskohlii has been chosen to establish scientific data for its traditional claim as anti-cancer. In the present study a chemical test performed against all the phytochemical constituents for their preliminary screening of each solvent extract of leaf like water, methanol, chloroform, ethyl acetate, and acetone. From the phytochemical investigation of the leaf extracts contains carbohydrates, glycosides, tannins, flavonoids, triterpenoids, and lipids in all the solvent extracts. But phenols are more retain in methanolic leaf extract remain all the phytochemical constituents.